Avian Lymphoid Leukosis (ALL) is a neoplastic disease caused by the Avian Leukosis Virus (ALV), primarily affecting chickens. It is a retroviral infection that causes tumors and various systemic effects, significantly impacting commercial poultry production.

SYMPTOMS
CAUSES
PREVENTION
TREATMENT

Symptoms

  • Primary Manifestations in Chickens:
    • Tumors in various organs (especially liver and bursa)
    • Depression and lethargy
    • Weight loss
    • Pale combs and wattles
    • Reduced egg production
    • Increased mortality after 16 weeks of age
    • Enlarged abdomen
    • Anemia
  • Note:
    • While primarily affecting chickens, other poultry species are generally resistant to the disease.

Causes and modes of transmission

  • Viral Characteristics:
    • Retrovirus (ALV)
    • Multiple subgroups (A, B, C, D, E, J)
    • Highly persistent in environment
  • Transmission Routes:
    • Vertical (through egg to offspring)
    • Horizontal (direct contact)
    • Contaminated equipment
    • Mechanical vectors
    • Congenital transmission

Prevention strategies

  • Breeding Management:
    • Testing and elimination of positive breeders
    • Eradication programs
    • Clean egg program
  • Biosecurity Measures:
    • Isolation of affected flocks
    • Proper cleaning and disinfection
    • Control of mechanical vectors
    • Regular testing programs
  • Management Practices:
    • All-in-all-out production
    • Proper disposal of affected birds
    • Monitoring programs
    • Record keeping

Treatment options

  • Direct Treatment:
    • No specific treatment available
    • Affected birds should be culled
    • Focus on prevention
  • Control Measures:
    • Regular surveillance
    • Removal of affected birds
    • Cleaning and disinfection
    • Testing of breeding stock

Conclusion:
Prevention through breeding programs and biosecurity is the only effective approach to controlling ALL, as there is no effective treatment once birds are infected.